Ectopic Parathyroid Adenoma in the Framework of an MEN1

Multiple endocrine neoplasia type 1 (MEN1 or Wermer syndrome) is a rare hereditary disease, and especially its association with ectopic parathyroid adenomas even more. Defined As tumor developing in at least two glands including the anterior pituitary gland, duodeno-pancreatic tissue. This autosomal dominant pathology caused by mutation of NEM1 gene encoding suppressor menin located on chromosome 11q13. There is, however, sporadic cases account for 8 to 14%. Primary hyperparathyroidism frequent secondary autonomous overproduction PTH (parathyroid hormone); it mostly due (solitary multiple). Diagnosis purely biochemical. Cervical ultrasound MIBI scintigraphy most often performed first line good diagnostic performance, surgery only curative treatment primary hyperparathyroidism, reason why preoperative localization best per-operative detection case an adenoma ensure proper resection avoid subsequent recurrences.